Plasma Concentration Studies
MOTS-C
Mitochondrial ORF of the 12S rRNA type-c
MRWQEMGYIFYPRKLR
A mitochondrial-derived peptide that modulates metabolic processes, with significant implications for exercise metabolism observed in rodent studies. Premium Research Peptide.
99%+ Purity
Purity Tested
Research Use Only
Laboratory Use
Peptide Profile
Peptide Type
Certificate of Analysis
Third Party Tested by Freedom Diagnostics
Compound Information
Technical specifications
What Is MOTS-c?
Stability Information
Extremely temperature sensitive. Store frozen until use. Reconstitute immediately before injection
Lyophilized (powder)
-20°C • stable long-term
Reconstituted
2-8°C • use immediately
Room temperature
Degrades 85-90% in 2-3 hrs
Sources & References
Peer-reviewed research
Cell Metabolism
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity...
2015 • DOI: 10.1016/j.cm...
PMID: 25738459
Lee C, Zeng J, Drew BG et al.
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Nature Communications
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and...
2021 • DOI: 10.1038/s41467-020-20790...
Reynolds JC, Lai RW, Woodhead JST et...
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Alzheimer's Drug Discovery Foundation
MOTS-c Cognitive Vitality Report
2021
ADDF Aging and Alzheimer's
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Aging Cell
The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?
2015 • DOI: 10.1111/acel.1...
PMID: 26289118
Fuku N, Pareja-Galeano H, Zempo H e...
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Physiol Rep
The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin...
2019 • PMID: 31293078
Kim S-J, Miller B, Mehta HH et al.
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Biochemical and Biophysical Research Communications
Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation
2016
Ming W, Lu G, Xin S et al.
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Pediatric Diabetes
Circulating MOTS-c levels are decreased in obese male children and adolescents and associated with...
2018
Du C, Zhang C, Wu W et al.
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ClinicalTrials.gov
Study of CB4211 in Patients With Nonalcoholic Fatty Liver Disease (NAFLD) and Obesity
2019
CohBar, Inc.
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