Plasma Concentration Studies
BPC-157/TB-500 (Wolverine)
Wolverine Blend
BPC + TB4
Regenerative Peptide Stack
Body Protection Compound + Thymosin Beta-4
A synergistic peptide combination designed to support tissue repair and regenerative processes through complementary cellular mechanisms in animal research models. Premium Research Peptide.
99%+ Purity
Purity Tested
Research Use Only
Laboratory Use
Peptide Profile
Peptide Type
Certificate of Analysis
Third Party Tested by Freedom Diagnostics
Compound Information
Technical specifications
Body Protection Compound-157
Thymosin Beta-4 (Fragment)
Stability Information
Protect from light. Avoid repeated freeze-thaw. Blue color indicates copper binding.
Light sensitive
Temperature sensitive
Lyophilized (powder)
-20°C • protect from light
Reconstituted
2-8°C
Sources & References
Peer-reviewed research
GlobalRPH Clinical Review
BPC-157 and TB-500: Background, Indications, Efficacy, and Safety
2025
McAuley D
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HSS Journal (NIH/PubMed Central)
Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review
2025 • DOI: 10.1177/15563316251355551
Vasireddi N, Hahamyan H, Salata MJ,...
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Expert Opinion on Biological Therapy
Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications
2012 • DOI: 10.1517/14712598.2012.634793
PMID: 22074294
Goldstein AL, Hannappel E, Sosne G, Kleinman HK
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Annals of the New York Academy of Sciences
A randomized, placebo-controlled, single and multiple dose study of intravenous thymosin beta4 in healthy volunteers
2010 • DOI: 10.1111/j.1749-6632.2010.05474.x
PMID: 20536472
Ruff D, Crockford D, Girardi G, Zhang Y
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Journal of Investigative Dermatology
Thymosin beta4 accelerates wound healing
1999 • 10.1046/j.1523-1747.1999.00708.x
PMID: 10469335
Malinda KM, Sidhu GS, Mani H, Banaudha K, Maheshwari RK, Goldstein AL, Kleinman HK
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Journal of Applied Physiology
The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration
2011 • DOI: 10.1152/japplphysiol.00945.2010
PMID: 21030672
Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH
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Scientific Reports (Nature)
Modulatory effects of BPC 157 on vasomotor tone and the Src-Cav-1-eNOS signaling pathway in rats
2020 • DOI: 10.1038/s41598-020-74022-y
PMID: 33046803
Hsieh MJ, Lee CH, Chueh HY, et al.
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Regulatory Toxicology and Pharmacology
Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds
2020 • DOI: 10.1016/j.yrtph.2020.104665
PMID: 32334036
Xu C, Sun L, Ren F, et al.
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Nature
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
2004 • DOI: 10.1038/nature03000
PMID: 15565145
Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D
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Growth Hormone & IGF Research
PCO-02 - Safety and Pharmacokinetics Trial (Phase 1)
2018 . DOI: 10.1016/j.ghir.2018.02.001
Staresinic M, Sebecic B, et al.
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International Journal of Molecular Sciences (PMC)
Progress on the Function and Application of Thymosin β4
2021 • DOI: 10.3390/ijms222413136
Xing Y, et al.
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ClinicalTrials.gov
PCO-02 - Safety and Pharmacokinetics Trial (Phase 1)
2015
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Combined Literature (Meta)
BPC-157 (200+ studies) and TB-500 (170+ citations) combined research base
2025
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